TRIOLEYL PHOSPHATE
Trioleyl phosphate acts as a plasticizer, solubilizer and dispersant.
Trioleyl phosphate improves solubility and dispersibility of self-emulsifying oils in a preparation.
Trioleyl phosphate is used in cosmetic care products.
CAS: 3305-68-8
European Community (EC) Number: 221-983-4
IUPAC Name: tris[(Z)-octadec-9-enyl] phosphate
Molecular Formula: C54H105O4P
Molecular Weight: 849.4 g/mol
Trioleyl phosphate, 3305-68-8, Hostaphat KO 300, tris[(Z)-octadec-9-enyl] phosphate, 04N84W7M6Y, UNII-04N84W7M6Y, EINECS 221-983-4, NIKKOL TOP-0, SCHEMBL304774, TRIOLEYL PHOSPHATE [INCI], SVETUDAIEHYIKZ-IUPFWZBJSA-N, NS00014186, 9-Octadecen-1-ol, phosphate (3:1), (Z,Z,Z)-, Q27247658, 9-OCTADECEN-1-OL, PHOSPHATE (3:1), (9Z,9'Z,9''Z)-, 9-OCTADECEN-1-OL, 1,1',1''-PHOSPHATE, (9Z,9'Z,9''Z)-
Trioleyl phosphate, also known as phosphoric acid trioleyl ester, is a chemical compound used in various applications.
Trioleyl phosphate is often used in cosmetics as an emollient, plasticizer, and skin conditioning agent.
The molecular formula of Trioleyl phosphate is C54H105O4P.
Trioleyl phosphate is a complex organic compound with three oleic acid residues attached to a single phosphorus atom.
Trioleyl phosphate is a liquid at 20 degrees Celsius.
Trioleyl phosphate has a specific gravity of 0.88 at 20/20 degrees Celsius and a refractive index of 1.47.
Trioleyl phosphate's flash point is 225 degrees Celsius.
While specific future directions for Trioleyl phosphate are not detailed in the search results, it is noted that it is used in cosmetics and could potentially find more applications in this and other industries.
Physical Properties
Boiling Point: 805.23 °C. at 760.00 mm Hg (est)
Flash Point: 847.00 °F. TCC ( 452.70 °C. ) (est)
logP (o/w): 25.027 (est)
Density: 0.9±0.1 g/cm3
Boiling Point: 805.2±64.0 °C at 760 mmHg
Vapour Pressure: 0.0±2.8 mmHg at 25°C
Enthalpy of Vaporization: 113.0±3.0 kJ/mol
Flash Point: 452.7±54.3 °C
Index of Refraction: 1.472
Molar Refractivity: 264.5±0.3 cm3
#H bond acceptors: 4
#H bond donors: 0
#Freely Rotating Bonds: 51
Trioleyl phosphate's functions
Emollient: Softens and softens the skin
Plasticizing Agent: Softens and makes flexible another substance that otherwise could not be easily deformed, dispersed or worked with
Skin care agent: Maintains skin in good condition
What does TRIOLEYL PHOSPHATE do in a formulation?
- Emollient
- Plasticiser
- Skin conditioning
Use:
Spray plasticizer: Trioleyl phosphate improves solubility and dispersibility of autolytic emulsified oils in formulations; vegetable source.
Plasticizer for sprays: Trioleyl phosphate improves solubility and dispersibility of self-emulsifying oils in a preparation; plant-derived.
Scientific Research Applications
Glycolytic Enzyme Activity and Neuropathy Research
Trioleyl phosphate, particularly in its form as triorthocresyl phosphate, has been studied for its effects on glycolytic enzymes during the development of organophosphate-induced delayed neuropathy.
Hernández, Pla, and Villanueva (1989) found that only phosphofructokinase activity decreased 15 days after treatment in sciatic nerve, while brain enzyme activity was unaffected.
This indicates its potential use in studying specific enzyme activities related to neuropathic conditions.
Neuropathological Effects Studies
In another study, investigated the neuropathological effects of triortho cresyl phosphate in hens, revealing changes in synapses and nerve fibers, indicating its use in neuropathological research.
Respiratory System Research
Silver, Leith, and Murphy (1981) studied the potentiation by triorthotolyl phosphate of acrylate ester-induced alterations in respiration, highlighting its application in respiratory irritancy and respiratory system studies.
Diabetes-Related Research
Babaei‐Jadidi et al. (2003) discussed the accumulation of triosephosphates in hyperglycemia and its link to diabetic nephropathy, indicating the application of trioleyl phosphate in diabetes research, particularly in studying biochemical dysfunctions leading to diabetic complications.
Cancer Research
Feun et al. (1984) conducted a Phase I trial of tricyclic nucleoside phosphate, demonstrating its application in advanced cancer research.
Effects on Phosphorus and Cholesterol Levels
Müller et al. (2007) studied the effect of Niaspan on serum phosphate and HDL cholesterol in dialysis patients, showcasing trioleyl phosphate's use in studying the impact on phosphorus and cholesterol levels in medical conditions.
Phosphate Therapy in Diabetic Ketoacidosis
Fisher and Kitabchi (1983) conducted a study on phosphate therapy in the treatment of diabetic ketoacidosis, which can be relevant for understanding the role of phosphates in managing this diabetic complication.
Phosphorus Source and Plant Growth
Asmah (1995) explored the effects of phosphorus sources, including phosphate rock, on the growth and nutrient content of maize, suggesting an application in agricultural research.